Comparative Analysis of Cytomorphology in Adolescent and Geriatric Patients: A Cross-Sectional Study

Background Exfoliation of the surface cells normal epithelium occurs as a result physiological turnover. Epithelial are constantly renewed, and they exfoliated or shed migrate from basal layer to uppermost epithelium. Oral exfoliative cytology involves collection microscopic evaluation these scraped epithelial cells, quantitatively qualitatively. The objective present study was analyze compare cytomorphometric features like cellular area, nuclear nuclear-cytoplasmic ratio buccal mucosal smears adolescent geriatric patients. This highlights changes in cell morphology different age groups (adolescent pediatric), which could be attributed hormonal, habitual, aging factors. Material methods Buccal smear sample collected total 60 individuals belonging 11-19 years above years. were stained with H&E PAP (Papanicolaou) stain. Photomicrographs taken 40x, measurements calculated using ImageJ software (National Institutes Health, Bethesda, Maryland, United States). Cellular size, nucleo-cytoplasmic analyzed compared between two independent t-tests IBM SPSS Statistics for Windows, Version 22.0 (Released 2013; Corp., Armonk, New York, Results A significant difference observed area p-value 0.00. No findings groups. Conclusion Cytomorphometric analysis has shown that there variations cytoplasmic areas among